Drug Safety Triager

The system is configurable to meet the workflow needs and the labelling desired by the customer. It provides timeliness tracking and quality control. The system assures Day zero visibility, including for changes related to full text, translation and author follow-up use and upload. The assessments’ output is compliant: ICSR are sent in E2B R3 to case processing, and Aggregate Reports are created in Vancouver style.

Dialog Solution’s artificial intelligence engine DialogML is part of the Dialog platform. It uses Natural Language Processing to enhances Dialog alerts by automatically identifying references in scientific literature that meet the criteria for ICSR, Aggregate Reports or Safety Signals.

DialogML applies a patient safety relevancy ranking to each reference and adds drug safety tags. As a result, in the Drug Safety Triager the most relevant and time-sensitive references are presented at the front of the queue and have the drug safety relevant terms highlighted. With DialogML assistance, literature review teams can find ICSRs 5x faster and reduce the volume of literature to be reviewed for ICSRs by up to 50% without introducing additional risk.

Drug Safety Triager automatically imports references from Dialog and other literature providers. The system auto-deduplicates at import and consolidates references retrieved for multiple drugs. Additional manual deduplication allows users to reduce further articles needing review.

An automated workflow ensures references can be reviewed step-by step by multiple users for multiple purposes in an organised and transparent way. Automated work allocation and advancement of articles with step validation checks along the process enable all users to work independently and with full accountability.

Drug Safety Triager features a range of configurable dashboards that help increase oversight of even the largest drug safety monitoring workflows. The dashboard cards provide quick access to targeted statistics for an immediate view of work status, including potential risks, priorities and longer-term trends in the review workflow. Easy to use, configurable features allow the administrator role to be performed by either a business or an IT professional.

Administrator self-serve features include self-setup and configuration by the administrator, full control over account creation and user access, and admin changes during the trial. Ad-hoc importing of additional literature outside of scheduled alerts is also included.

Drug Safety Triager is proven to deliver measurable efficiencies and cost savings through deduplication, multi-drug review, prioritization and reference review time reduction enabled by the AI assistant, bulk review, easily accessible SOP links and supporting documents, and an intuitive and streamlined interface. The best-practice workflow reduces irrelevant literature references to be reviewed for Aggregate Reporting and Signal detection by up to 70%.